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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: J Invest Dermatol. 2014 Nov 14;135(6):1540–1547. doi: 10.1038/jid.2014.485

Figure 2. Prominent white nails and progressive keratoderma in EKVP due to GJA1 mutation.

Figure 2

All subjects show prominent porcelain white proximal nails without dystrophy. Honeycombed thick hyperkeratosis is present on the palms, and similar thick hyperkeratosis is present on the feet. Keratoderma is progressive with 30-month-old 101-1 (a), showing less hyperkeratosis than 6-year-old 102-1 (b) or 30-year-old 103-1 (c). Subject 103-1 is on a systemic retinoid, accounting for peeling seen at lateral aspects of hand and foot and less exuberant hyperkeratosis.