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. Author manuscript; available in PMC: 2016 Jun 10.
Published in final edited form as: J Control Release. 2015 Mar 31;207:7–17. doi: 10.1016/j.jconrel.2015.03.034

Fig. 6.

Fig. 6

Sequential delivery of VEGF and PDGF improves angiogenesis 4 wks after MI. (A) Representative images show co-staining of VWF (red) and α-SMA (green) that reflect the level of neovessel formation, their functionality and maturity, with noticeable improved angiogenesis in the sequential delivery group. (B) Saline and empty vehicle groups showed little angiogenesis with few VWF-positive vessels. While free GFs induced significantly more VWF-positive vessels than controls, sequential delivery induced significantly more than all groups. (C) Sequential delivery induced significantly more α-SMA-positive vessels than all groups. Data are presented as means ± SD (n=4–5 per group). *P<0.05, **P<0.01. Scale bar=200 µm.