Table 4. Sensitivity, specificity, positive and negative predictive values and likelihood ratios for being impaired on both the Alberta Infant Motor Scale and the Neuro-Sensory Motor Developmental Assessment at 4, 18 and 12 months for predicting motor impairment at 4 years.
Age at assessment | Delayed on the predictor n (%) | Motor outcome at 4 years | Impaired on the outcome n (%) | Sensitivity (95%CI) | Specificity (95%CI) | +ve PV (95%CI) | -ve PV (95%CI) | LR+ (95% CI) | LR- (95% CI) | Accuracy % (95% CI) |
---|---|---|---|---|---|---|---|---|---|---|
4 months | 11 (13%) | MABC<15th | 21 (26%) | 38 (18, 62) | 95 (86, 99) | 73 (39, 94) | 82 (71, 90) | 7.7 (2.3, 26.5) | 0.7 (0.5, 0.9) | 80 (70, 88) |
MABC<5th | 18 (22%) | 44 (22, 69) | 95 (87, 99) | 73 (39, 94) | 86 (76, 93) | 9.5 (2.8, 32.1) | 0.6 (0.4, 0.9) | 84 (74, 91) | ||
CP | 6 (7%) | 83 (36, 100) | 93 (85, 97) | 45 (17, 77) | 99 (93, 100) | 11.3 (4.8, 26.3) | 0.2 (0.0, 1.1) | 92 (84, 97) | ||
8 months | 19 (22%) | MABC<15th | 21 (26%) | 52 (30, 74) | 89 (78, 95) | 61 (36, 83) | 84 (73, 92) | 4.6 (2.0, 10.2) | 0.5 (0.3, 0.9) | 79 (69, 87) |
MABC<5th | 18 (22%) | 56 (31, 78) | 88 (77, 94) | 56 (31, 78) | 88 (77, 94) | 4.4 (2.1, 9.6) | 0.5 (0.3, 0.9) | 80 (70, 88) | ||
CP | 6 (7%) | 100 (54, 100) | 84 (74, 91) | 32 (13, 57) | 100 (95, 100) | 6.2 (3.8, 10.3) | * | 85 (76, 92) | ||
12 months | 14 (16%) | MABC<15th | 21 (26%) | 38 (18, 62) | 92 (82, 97) | 62 (32, 86) | 81 (70, 90) | 4.6 (1.7, 12.6) | 0.7 (0.5, 1.0) | 78 (68, 86) |
MABC<5th | 18 (22%) | 39 (17, 64) | 91 (81, 96) | 54 (25, 81) | 84 (73, 92) | 4.1 (1.6, 10.8) | 0.7 (0.5, 1.0) | 79 (69, 87) | ||
CP | 6 (7%) | 100 (54, 100) | 90 (81, 96) | 43 (18, 71) | 100 (95, 100) | 10.1 (5.2, 19.5) | * | 91 (83, 96) |
Note-CI = Confidence Interval, CP = Cerebral Palsy, MABC = Movement Assessment Battery for Children-2nd edition; PV = Predictive Value; LR = Likelihood Ratio; Results are all percentages except for LR; Numbers in bold reflect the most accurate assessment for each outcomes
* Cannot calculate the LR- when the—ve PV is 100%