Table 4. Relationship of 25-hydroxyvitamin D concentration (per 10 nmol/L) to the histopathological indicators of melanoma prognosis with adjustment for confounding factors.
Model | Crude OR | 95% CI | P-value | Adjusted OR | 95% CI | P-value |
---|---|---|---|---|---|---|
Breslow thickness(≥0.75 mm) | 0.75 | 0.54, 1.02 | 0.07 | 0.78 a | 0.55, 1.11 | 0.17 |
Clark level(Levels 2–5) | 0.88 | 0.72, 1.09 | 0.26 | 0.93 b | 0.71, 1.22 | 0.60 |
Mitotic activity(present) | 0.91 | 0.71, 1,17 | 0.47 | 0.96 c | 0.70, 1.33 | 0.82 |
OR: odds ratio; CI: confidence interval.
a Adjusted for age, sex, ITA value, BMI, season at diagnosis
b Adjusted for age, sex, ITA value, BMI, season at diagnosis, naevi burden at diagnosis, number of primary school sunburns
c Adjusted for age, sex, ITA value, BMI, season at diagnosis, naevi burden at diagnosis, number of primary school sunburns