A, Serum insulin measured at cycle 5 from female OVX+V or OXV+E mice subjected to JL or RC; n = 6–7 per group. Data are presented as mean ± SEM. *, P < .05; **, P < .01; NS, no significance in two-way ANOVA analyses followed by post hoc Bonferroni tests. B, GTT performed at cycle 3; n = 6–7 per group. Data are presented as mean ± SEM. *, P < .05 or **, P < .01 between OVX+V JL and OVX+V RC; !, P < .05 between OVX+V JL and OVX+E JL; #, P < .05 between OVX+V RC and OVX+E RC in two-way ANOVA analyses followed by post hoc Bonferroni tests. C, Area under the curve (AUC) for GTT data in B; n = 6–7 per group. Data are presented as mean ± SEM. *, P < .05; NS, no significance in two-way ANOVA analyses followed by post hoc Bonferroni tests. D, ITT performed at cycle 4; n = 6–7 per group. Data are presented as mean ± SEM. *, P < .05 or **, P < .01 between OVX+V JL and OVX+V RC; !, P < .05; !!, P < .01; or !!!, P < .001 between OVX+V JL and OVX+E JL in two-way ANOVA analyses followed by post hoc Bonferroni tests. E, AUC for ITT data in D; n = 6–7 per group. Data are presented as mean ± SEM. *, P < .05; NS, no significance in two-way ANOVA analyses followed by post hoc Bonferroni tests.