Table 5.
The results of receiver operating characteristic (ROC) curve analysis for dynamic variables.
| ROC-AUC | p value | Cut-off value | Sensitivity | Specificity | 95% confidence interval | |
|---|---|---|---|---|---|---|
| WBC1-WBC2 (×103/uL) | 0.73 | 0.004 | 3570 | 70% | 77% | 0.59–0.88 |
| WBC3-WBC2 (×103/uL) | 0.84 | <0.001 | 195 | 78% | 77% | 0.7–0.98 |
| PMN1-PMN2 (×103/uL) | 0.69 | 0.02 | 1938 | 73% | 70% | 0.53–0.86 |
| PMN3-PMN2 (×103/uL) | 0.90 | <0.001 | −243 | 84% | 86% | 0.81–0.99 |
| Lymph1-Lymph2 (×103/uL) | 0.65 | 0.09 | — | — | — | — |
| Lymph3-Lymph2 (×103/uL) | 0.65 | 0.08 | — | — | — | — |
| Hgb1-Hgb2 (g/dL) | 0.72 | 0.008 | 0.55 | 76% | 68% | 0.58–0.85 |
| Hgb3-Hgb2 (g/dL) | 0.52 | 0.8 | — | — | — | — |
| PLT1-PLT2 (/microliter) | 0.78 | 0.001 | 30000 | 82% | 60% | 0.67–0.90 |
| PL3-PLT2 (/microliter) | 0.92 | <0.001 | 97000 | 78% | 90% | 0.85–1.00 |
| ESR1-ESR2 (mm/h) | 0.69 | 0.02 | 9 | 64% | 56% | 0.54–0.85 |
| ESR3-ESR2 (mm/h) | 0.80 | 0.002 | −4.5 | 75% | 86% | 0.63–0.97 |
| CRP1-CRP2 (mg/L) | 0.77 | 0.003 | 42.5 | 76% | 67% | 0.64–0.89 |
| CRP3-CRP2 (mg/L) | 0.53 | 0.5 | — | — | — | — |
ROC-AUC: receiver operating characteristic-area under the curve, MAS: Macrophage Activation Syndrome, WBC: white blood cells, PMN: polymorphonuclear, Lymph: lymphocytes, Hgb: hemoglobin, PLT: platelet, ESR: erythrocyte sedimentation rate, and CRP: C-reactive protein. The previous laboratory records: WBC1, PMN1, and so forth. The laboratory data at the onset of MAS (MAS group) or active rheumatologic disease (control group): WBC2, PMN2, and so forth. The laboratory data 1 month after discharge from the hospital: WBC3, PMN3, and so forth.