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Correcting for lymphoid content reveals an upregulation of stroma-related genes in nodal metastasis compared with primary tumours. (A) Estimate of the fraction of normal lymphoid tissues in nodal metastasis samples (calculation explained in Material and Methods and illustrated in Supplementary Figure S1). (B) Same as in Figure 3A, except that expression profiles of nodal metastases were adjusted for normal lymphoid tissue content.
