Table 3. The distribution of prognostic factors between HER2-positive and HER2-negative ctDNA samples.
HER2-positive in ctDNA | HER2-negative in ctDNA | P-value | |
---|---|---|---|
Number of patients | 7 | 17 | |
Age (years, median (range)) | 67 (60–76) | 64 (29–81) | 0.464 |
Sex | |||
Male | 6 | 13 | 0.612 |
Female | 1 | 4 | |
Tumour stage | |||
III | 0 | 1 | 0.512 |
IV | 7 | 16 | |
Histology | |||
Intestinal type | 5 | 7 | 0.177 |
Diffuse type | 2 | 10 | |
HER2 with IHC/FISH | |||
Positive | 4 | 4 | 0.112 |
Negative | 3 | 13 |
Abbreviations: ctDNA=circulating tumour DNA; FISH=fluorescence in situ hybridisation; HER2=human epidermal growth factor receptor 2; IHC=immunohistochemistry.