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Time course of CIGB-300 tumour uptake. In the first day of cycle 1, 35 or 70 mg of 99mTc-radiolabelled CIGB-300 was injected directly into tumours and whole-body gammagraphic images were taken during 24 h after administration. CIGB-300 tumour uptake is expressed as mg of CIGB-300 retained in tumours. S.e.m. is represented. Inset corresponds to a illustrative anterior whole-body image from one patient at 10 min after injecting 70 mg (group II) of radiolabelled peptide.
