Table 1.
Patient demographics
| ALPPS (n = 15) | PVE (n = 53) | LD (recip) (n = 90) | LD (donor) (n = 93) | P value (ALPPS versus PVE) | |
|---|---|---|---|---|---|
| Age (years) | 55.9 ± 12.1 | 59.5 ± 11.3 | 50.1 ± 12.8 | 38.0 ± 9.2 | 0.29 |
| Gender(male) | 11 (73%) | 31 (58%) | 56 (62%) | 41 (44%) | 0.3 |
| BMI | 26.2 ± 4.2 | 27.9 ± 6.8 | 27.6 ± 5.4 | 25.6 ± 3.5 | 0.36 |
| Diabetes | 1 (7%) | 4 (8%) | 12 (13%) | 1 (1%) | 0.91 |
| Diagnosis | |||||
| CRLM | 14 (93%) | 37 (70%) | NA | NA | 0.06 |
| Cholangiocarcinoma | 0 | 7 (13%) | NA | NA | 0.14 |
| HCC | 0 | 2 (4%) | NA | NA | 0.45 |
| Other | 1 (7%) | 7 (13%) | NA | NA | 0.49 |
| Transplant Indication | |||||
| Cholangiocarcinoma | NA | NA | 36 (40%) | NA | NA |
| PSC | NA | NA | 20 (22%) | NA | NA |
| Hepatitis C | NA | NA | 5 (6%) | NA | NA |
| NASH | NA | NA | 4 (4%) | NA | NA |
| Other | NA | NA | 25 (28%) | NA | NA |
| Chemotherapy | 14 (93%) | 40 (75%) | NA | NA | 0.13 |
| Failure to complete planned resection | 0 | 11 (21%) | NA | NA | 0.05 |
| 50/50 Criteria | 2 (13%) | 12 (29%)a | NA | 13 (14%) | 0.24 |
| Peak bilirubin >7 mg/dl | 2 (13%) | 4 (10%)a | NA | 3 (3%) | 0.68 |
| 90 day mortality | 0 (0%) | 2 (5%)a | 3 (3%) | 0(0%) | 0.39 |
BMI, body mass index; HCC, hepatocellular carcinoma; LD, living donor; NASH, non-alcoholic steatohepatitis; PSC, primary sclerosing cholangitis; PVE, portal vein embolization.
a
= of 42 patients that completed the planned resection.