Table 1.
Correlation of cytokine/chemokine levels with bacterial outgrowth of wild-type and C/EBPδ −/− mice upon meningitis
Brain (30 h after inoculation) | ||||
---|---|---|---|---|
Wild type | C/ EBPδ −/− | |||
(n = 11) | (n = 12) | |||
Cytokines | ( r 2 ) | P value | ( r 2 ) | P value |
IL-6 | 0.7223 | 0.0009 | 0.0499 | 0.4853 |
TNF-α | 0.3922 | 0.0393 | 0.4356 | 0.0271 |
IL-1β | 0.3922 | 0.0393 | 0.4356 | 0.0271 |
IL-10 | 0.5679 | 0.0074 | 0.0405 | 0.5303 |
Chemokines | ||||
KC | 0.8320 | <0.0001 | 0.2704 | 0.1011 |
MIP-2 | 0.8405 | <0.0001 | 0.6779 | 0.0010 |
Data were obtained using a Pearson correlation analysis and presented as linear regression values for each group (r 2) and concomitant P values. Significant correlations (P < 0.05) are in italic. Non-significant values are shown in gray.