Table 2.
Effect of resveratrol supplementation (RSV) on fasting blood sugar levels and insulin levels
| Healthy | Diabetic | Diabetic RSV 1 mg/kg | Diabetic RSV 5 mg/kg | Diabetic RSV 10 mg/kg | P value** | |
|---|---|---|---|---|---|---|
| Pretreatment day 0 | 87.3±10.6 | 95.62±7.3 | 93.2±14.8 | 84.1±11.0 | 90.5±7.23 | 0.27 |
| 7days after diabetes induction | 89.12±10.7 | 279.2±95.3a# | 289.7±79.2a# | 219.3±120a* | 241.2±99.8a* | 0.001 |
| One month after treatment | 92.0±10.8 | 303.3±92.1a* | 271.3±77.5a# | 192.5±84.8b* | 190.3±68.6b* | <0.001 |
| Insulin (μU/ml) | 11.17±1.06 | 7.23±1.15a# | 8.13±0.97a# | 9.52±1.05b# | 9.83±0.86b#,c* | <0.001 |
| HOMA | 2.51±0.37 | 5.46±2.09a* | 5.52±1.92a* | 3.73±2.01b# | 4.77±1.08b#,c* | 0.01 |
Mean±SD FBS, Insulin and HOMA in healthy (n=8) and diabetic control groups (n=8) and RSV-treated diabetic rats (1, 5, 10 mg/kg, n=8). a: Compared with healthy control; b: Compared with diabetic control; c: Compared with diabetic rats treated with resveratrol 1 mg/kg; *P<0.05; #P<0.001; **Comparison between all groups