Table 4.
Effect of resveratrol supplementation (RSV) on expression of SNAP23, Syntaxin-4 and VAMP-2 (∆ct)
| Healthy | Diabetic | Diabetic RSV 1 mg/kg | Diabetic RSV 5 mg/kg | Diabetic RSV 10 mg/kg | P value** | |
|---|---|---|---|---|---|---|
| Syntaxin-4 | 12.16±1.10b# | 15.11±1.58a# | 11.17±1.60b# | 13.28±0.77b#,c* | 12.92±1.44b# | <0.001 |
| Vamp-2 | 8.53±1.82b# | 11.48±2.7a# | 6.99±1.40b# | 9.98±1.55b# | 9.39±1.40b# | <0.001 |
| SNAP-23 | 4.18±1.42b# | 8.65±3.3 a# | 3.98±0.83b# | 4.98±2.22b# | 4.78±1.46b# | <0.001 |
Mean±SD ∆Ct in health (n=8), diabetic control groups (n=8) and RSV-treated diabetic rats (1, 5, 10 mg/kg, n=8). a: Compared with healthy control; b: Compared with diabetic control; c: Compared with diabetic rats treated with resveratrol 1 mg/kg; *P<0.05; #P<0.001; **Comparison between all groups