Table 4.
Clinical studies applying allogeneic mesenchymal stromal cells to a cartilage defect for repair
| Cell type | Number of patients | Follow-up | Results | Reference |
|---|---|---|---|---|
| UMSC | 104 | 48 weeks | Safe application and repair with hyaline tissue | [20] NCT01041001 |
| UMSC | 103 | 60 months | NCT01626677 | |
| UMSC | 12 | 24 months | NCT01733186 | |
| SMSC | [16,17] | |||
| BMMSC with AC | 35 | 1 year | Preliminary: safe application and repair with hyaline tissue | [3,46] NCT02037204 |
AC autologous chondrons, BMMSC bone marrow-derived mesenchymal stromal cell, SMSC synovium-derived mesenchymal stromal cell, UMSC umbilical cord blood-derived mesenchymal stromal cell