Table 2.
In silico validation of the Xenopus NRSE screen with in situ hybridization and REST CHIP-seq. Putative REST target genes were categorized into neuronal/heart or non-neuronal/non-heart expression based on in situ hybridization data collected from Xenbase
| in situ hybridization | REST CHIP-Seq | |
|---|---|---|
| Neuronal/Heart Expression 141 genes | Non-neuronal/non-heart Expression | 57 genes |
| Bsx, arl6ip1, cox5a, ag1, cacna1h, adarb1, ahctf1, asb8, churc1, cpsf2, cpeb1, dact1, adprh, bmp7.1, bsn, cldn5, asap1, arid4a, cdca8, cdk1, calu, colec11, arl8a, bri3, admp, cdh12, arx, celf2, cdc45, cacna1a, col18a1, CACNA1C, calb1, clasp1, copg, crb2, dlx4, dmrta2, dnal4, dvl1, egr1, eif4h, elavl4, elk1, ephb1, erbb4, ern2, esr10, esyt2, ext1, fam54b, fgf12, frzb2, fzd3, gabbr2, gabra3, gabra5, gbx2.1, gbx2.2, gcat, gdf11, gdi1, gfi1, gjb1, glmn, gpr84, hes4, hnf4a, hnrnpa1, hpcal1, id2, igfbp4, insm1, ism1, kaz, klf11, klhdc4, lhx2, lhx3, lhx5, limk1, mef2d, mnt, mnx1, myl7, myo1c, myo1d, nbl1, ncoa5, nefm, neurod1, neurog3, nol10, nr2f2, pcdh10, pcmtd1, pla2g7, plxnb1, pnhd, pou4f1, prph, rab34, rab7a, rasip1, rax, rbm38, rgs20, rhbdd3, ric8a, rps3, scn2a, scn3a, selt, sema3a, siah2, slc32a1, slc3a2, slit1, smad4, smarca4, snai1, sox14, sphk1, spry2, srsf5, srsf6, supt6h, suv420h1, tbx5, tcea1, tmub2, tpm4, tubgcp4, vamp1, vav2, wdr5, wdr73, wdr74, wnt16, wnt3a, wnt9b | Alb, alg3, amy2b, anxa4, arf1, armc4, baiap2l1, bsg, col1a1, CREB3L2, ctsc, cxcr7, dazap1, dcdc2, fgf14, fuz, gamt, gfpt1, gorasp2, grhl1, gstp1, igsf9b, impdh1, iqgap1, iqgap2, itga8, klf5, krt5.7, laptm4a, ldlrap1, mmp9, mst1r, myos, nbn, ndufaf3, nodal, nom1, odc1, pcdh8, ppp1r3c.1, rab18, rab8a, rnd1, sept2, sept9, sfrp5, sgk2, snd1, sox17b.1, sox2, trappc2, tspan7, tspan8, ttll4, upk1b, ventx1.2, ventx2.1, ventx2.2, ypel5, zdhhc1, zdhhc4, zfpm1 | Angptl6, ap1s1, ap3b2, brsk2, bsx, cacna1a, cacna1h, cacna2d2, cdh22, cdb4, chd5, chat, cpsf3, cyp27b1, decr1, ebf1, fgf14, glra1, grin1, hes3, icmt, kcnc3, kcnh4, kndc1, lhx3, lhx5, lin37, march11, nefm, neto1, nr2f1, nup133, ogdh, olfm3, pafah1b1, pcgf6, pipox, plbd2, plbd2, pou4f1, ptk2b, pusl1, qsox2, rdh8, ric8b, rnf219, sdsl, slc35f4, slc4a1, slc4a1ap, slc5a11, syt4, taf5, vwc2l, xkr7, zcchc14, rasgrf1 |