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. 2015 May 12;5(5):e007375. doi: 10.1136/bmjopen-2014-007375

Table 4.

Associations between race/ethnicity and continuous HbA1c in the overall population and within individual drug regimens

Treatment Model 1*
Per cent difference (95% CI)
Model 2†
Per cent difference (95% CI)
Model 3‡
Per cent difference (95% CI)
Overall population (n=682)
 Black 6.18 (−1.00 to 12.75) 5.13 (−1.00 to 11.63) 6.18 (−1.00 to 13.88)§
 Hispanic 3.05 (−3.92 to 10.52) 3.05 (−3.92 to 9.42) 1.01 (−9.52 to 12.75)§
 White Reference Reference Reference
Biguanides only (n=174)
 Black 11.63 (1.01 to 22.14) 11.63 (1.01 to 24.61) 3.05 (−5.82 to 12.75)
 Hispanic 9.42 (−1.00 to 19.72) 9.42 (0.00 to 20.92) 10.51 (−2.96 to 25.86)
 White Reference Reference Reference
Insulin only (n=120)
 Black 10.52 (−5.82 to 28.40) 6.18 (−7.69 to 23.37) 4.08 (−5.82 to 15.03)
 Hispanic 10.52 (−5.82 to 28.40) 0.00 (−13.06 to 15.03) 8.33 (−14.79 to 37.71)
 White Reference Reference Reference
Biguanides combined with insulin or sulfonylureas (n=140)
 Black −1.98 (−14.79 to 11.63) 5.13 (−9.52 to 11.63) −0.09 (−13.85 to 15.86)
 Hispanic −2.96 (−14.79 to 10.52) 5.13 (−9.52 to 11.63) −2.96 (−16.47 to 12.75)
 White Reference Reference Reference
Other miscellaneous drug regimens (n=123)
 Black 11.63 (1.01 to 23.37) 10.52 (0.00 to 20.92) 23.37 (7.25 to 43.33)
 Hispanic 2.02 (−1.98 to 16.18) 1.01 (−11.31 to 15.03) 10.52 (−10.42 to 36.34)
 White Reference Reference Reference

*Estimates are adjusted for gender and age.

†Estimates are adjusted for gender, age and BMI.

‡Estimates are adjusted for gender, age, BMI, education, adequate health literacy, private insurance, income, physical activity, diet, caloric intake and DM duration.

§Additionally adjusted for treatment regimens: biguanides only, insulin only, biguanides combined with insulin or sulfonylureas, and other regimens.

BMI, body mass index; DM, diabetes mellitus; HbA1c, glycated haemoglobin.