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. 2015 Jun;105(6):e36–e43. doi: 10.2105/AJPH.2014.302487

TABLE 2—

Effect of Selected Exposures on the Incidence Rate of Hepatitis B Virus Infection Among Successfully Vaccinated Drug Users Over the 2-year Follow-Up, Long-Term Effectiveness of Accelerated Hepatitis B Vaccination Schedule

Predictor Variable Total (No.) No. With HBV Infection Person-Years Incidence Density Adjusted Relative Risk (95% CI)a P
Overall 707 10 1166 8.6 . . .
Vaccination schedule .053
 Standard 342 8 576 13.9 1.00 (Ref)
 Accelerated 365 2 590 3.4 0.21 (0.04, 1.02)
Age, y .422
 < 40 250 3 394 7.6 1.00 (Ref)
 ≥ 40 457 7 772 9.1 0.53 (0.11, 2.5)
Gender . . .
 Male 543 8 881 9.1
 Female 164 2 286 7.0
Race .293
 Non-African 59 1 130 7.7 1.00 (Ref)
 African American 616 9 1036 8.7 3.5 (0.34, 36.27)
Education . . . . . .
 ≤ high school 534 9 885 10.2
 > high school 173 1 281 3.6
HCV at enrollment 139 6 218 27.5 6.54 (1.49, 28.76) .013
MSM 47 1 71 14.2 1.63 (0.19, 13.96) .658
Past 30 d
 IDU 36 0 52 0 . . . . . .
 Crack 656 9 1090 8.3 . . .
 Cocaine 98 2 152 13.2 . . .
 Methamphetamine 22 0 39 0 . . .
 Fry 16 0 27 0 . . .
 Marijuana 345 4 563 7.1 . . .
 Alcohol 491 8 809 9.9 . . .
 Heroin 19 0 28 0 . . .
 Speedball 7 0 10 0 . . .
 Ever used injecting drugs 146 4 233 17.2 1.75 (0.38, 7.95) .47
No. drug use . . .
 < 2 138 0 224 0
 ≥ 2 569 10 942 10.6
Anti-HBs antibody (mIU/ml)b .176
 < 10 368 7 552.5 12.7 1.00 (Ref)
 ≥ 10 339 3 613.5 4.9 0.39 (0.1, 1.53)

Note. CI = confidence interval; HBs = hepatitis B; IDU = injecting drug use; MSM = men who have sex with men.

a

Cox proportional hazard regression.

b

At 12 months postenrollment.