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. 2015 May 8;8:46. doi: 10.1186/s13045-015-0143-3

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© Chau et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Methylation status of HNF1A promoter and correlation between the expressions of AQP9 and HNF1A in primary AML samples. (A) MSP showing highly methylated HNF1A promoter in 16 human AML samples. (B) Quantification of AQP9 and HNF1A expressions in 16 human AML samples. Result was analyzed using Pearson test. AQP9 level was found to correlate positively with HNF1A level (p = 0.0045).