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(A) Study design (double-blind period) and (B) patient disposition. ACR, American College of Rheumatology; AE, adverse event; CZP, certolizumab pegol; DMARDs, disease-modifying antirheumatic drug; MARVELOUS, MAgnetic Resonance image VErified earLy respOnse on rheUmatoid factor positive arthritiS; RA, rheumatoid arthritis.
