Table 3. SNP association of CAV1 and CAV2 expression.
Cell type (ethnicity) | n |
CAV1 |
CAV2 |
||
---|---|---|---|---|---|
β or ρa | p | β or ρa | p | ||
rs17588172
G | |||||
Adipose (CEU) |
856 |
−0.32 |
3.9×10−23 |
−0.11 |
0.00027 |
Skin (CEU) |
856 |
−0.22 |
3.0×10−18 |
−0.11 |
0.00014 |
LCL (CEU) |
856 |
−0.027 |
0.00013 |
0.045 |
4.9×10−8 |
LCL (CHB)a |
80 |
−0.11 |
0.33 |
0.68 |
2.8×10−12 |
LCL (JPT)a |
82 |
0.11 |
0.92 |
0.82 |
9.5×10−21 |
rs4236601
Ab | |||||
Adipose (CEU) |
856 |
−0.28 |
5.8×10−16 |
−0.067 |
0.031 |
Skin (CEU) |
856 |
−0.20 |
4.0×10−13 |
−0.11 |
0.00041 |
LCL (CEU) | 856 | −0.030 | 0.000085 | 0.0098 | 0.27 |
Standardized regression coefficient β values were calculated using the data from Grundberg et al. [21]. aFor Asian samples, Spearman's rank-order correlation coefficient ρ values rather than the β values were calculated using the data from Stranger et al. [22]. bThe β values for rs4236601 are consistent with those recently reported by Hysi et al. [16] but direction of the risk allele effect is additionally shown here. Abbreviations: eQTL, expression quantitative trait loci; CAV, caveolin; LCL, lymphoblastoid cell line; CEU, Caucasians in Europe; CHB, Chinese in Beijing; JPT, Japanese in Tokyo.