Figure 2. Modifications of goblet cells.

(a). Some mucus granules were more vacuolated in the colon of transgenic (Tg) mice. (b). The ileum of Tg mice harbored a higher number of goblet cells, as counted on AB-PAS tissue sections. (c). Electron microscopic analysis showing that the colon of transgenic (Tg) mice harbored goblet cells with the same average surface, but with fewer mucus granules compared with wild-type (WT) mice. Close examination showed that some mucus granules were merged.