Figure 5. The transgene protects against dextran sodium sulfate (DSS)-induced colitis.

(a). Wild-type (WT; n = 11) and transgenic (Tg, n = 9) mice were treated with 2.5% DSS or phosphate-buffered saline (PBS) for 5 days, and then received water for 7 days. Body mass was scored daily. (b). Histological score⁷⁶ was calculated at day 12. (c). Proliferating cell nuclear antigen (PCNA) immunostaining of colon sections and its quantification showed an increase in epithelial cell proliferation in Tg mice.