Table 1.
Association between expression level of DPYSL3 mRNA and clinicopathological parameters in 238 patients
| Variables | High DPYSL3 mRNA in GC tissue (n) | Low DPYSL3 mRNA in GC tissue (n) | P -value |
|---|---|---|---|
| Age | 0.793 | ||
| < 65 year | 51 | 49 | |
| ≥ 65 year | 68 | 70 | |
| Gender | 0.453 | ||
| Male | 87 | 92 | |
| Female | 32 | 27 | |
| Carcinoembryonic antigen (ng/ml) | 0.415 | ||
| ≤ 5 | 93 | 98 | |
| > 5 | 26 | 21 | |
| Carbohydrate antigen 19–9 (IU/ml) | 0.504 | ||
| ≤ 37 | 95 | 99 | |
| > 37 | 24 | 20 | |
| Tumor location | 0.769 | ||
| Entire | 12 | 8 | |
| Upper third | 24 | 27 | |
| Middle third | 37 | 35 | |
| Lower third | 46 | 49 | |
| Tumor size (mm) | 0.090 | ||
| < 50 | 48 | 61 | |
| ≥ 50 | 71 | 58 | |
| Tumor depth (UICC) | <0.001* | ||
| pT1-3 | 51 | 77 | |
| pT4 | 68 | 42 | |
| Histology | 0.098 | ||
| Papillary | 1 | 1 | |
| Well differentiated | 4 | 10 | |
| Moderately differentiated | 33 | 48 | |
| Poorly differentiated | 74 | 56 | |
| Signet ring cell | 5 | 2 | |
| Mucinous | 2 | 2 | |
| Differentiation | 0.006* | ||
| Differentiated | 39 | 60 | |
| Undifferentiated | 80 | 59 | |
| Lymphatic involvement | 0.016* | ||
| Absent | 11 | 24 | |
| Present | 108 | 95 | |
| Vessel invasion | 0.036* | ||
| Absent | 44 | 60 | |
| Present | 75 | 59 | |
| Infiltrative growth type | <0.001* | ||
| Invasive growth | 55 | 28 | |
| Expansive growth | 64 | 90 | |
| Lymph node metastasis | <0.001* | ||
| Absent | 32 | 57 | |
| Present | 87 | 62 | |
| Peritoneal lavage cytology | 0.001* | ||
| Negative | 84 | 104 | |
| Positive | 35 | 15 | |
| UICC stage | 0.032* | ||
| I - III | 77 | 92 | |
| IV | 42 | 27 |
Abbreviations: UICC Union for International Cancer Control. *Statistically significant (P < 0.05).