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. 2015 Apr 10;7(1):42. doi: 10.1186/s13148-015-0076-2

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© Costa-Pinheiro et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Expression of has-mir-375 is increased in prostate cancer and associates with lymph node stage in patients from TCGA. (A) miR-375 expression (TCGA miRNAseq RPKM level 3 value) was evaluated in 50 tumor and matched normal samples of prostate adenocarcinoma patients from TCGA. All tumor samples presented overexpression comparing to their matched normal samples (***P < 0.0001). (B) The expression of hsa-mir-375 (TCGA miRNAseq RPKM level 3 value) was assessed in 177 prostate adenocarcinoma patients from TCGA with lymph node stage information available. Patients in the N1 lymph node stage presented significantly higher expression of hsa-mir-375 than patients in the N0 stage.