Table 2.
Baseline demographic and drug use characteristics
| Total (N=171) | TOP/CM (N=40) | TOP/Non-CM (N=45) | P/CM (N=39) | P/Non-CM (N=47) | |
|---|---|---|---|---|---|
| Age, M (SD) | 42 (7) | 43 (7) | 41 (7) | 40 (8) | 42 (7) |
| Age 18–40, (%)* | 38 | 33 | 44 | 38 | 36 |
| Age 41–55, (%) | 62 | 68 | 56 | 62 | 64 |
| Race (% AA) | 60 | 58 | 60 | 54 | 68 |
| Gender (% F) | 48 | 43 | 49 | 49 | 51 |
| Education, M (SD) | 11 (1.7) | 11 (2.1) | 11 (1.4) | 12 (1.4) | 11 (1.7) |
| Education <12, (%) | 42 | 40 | 44 | 41 | 40 |
| Education ≥ 12, (%) | 58 | 60 | 56 | 59 | 60 |
| Marital Status (%) | |||||
| Never Married | 62 | 53 | 73 | 69 | 53 |
| Married | 13 | 10 | 9 | 15 | 19 |
| Separated/Divorced/Widowed | 25 | 38 | 18 | 15 | 28 |
| Employment (%) | |||||
| Employed | 26 | 33 | 22 | 28 | 23 |
| Unemployed/Disabled* | 74 | 68 | 78 | 72 | 77 |
| Transfer Methadone Maintenance** (%) | 36 (21) | 13 (33) | 9 (20) | 7 (18) | 7 (15) |
| Clinician CSSA Admission Score, M (SD) | 32 (19) | 34 (19) | 31 (17) | 32 (18) | 33 (20) |
| Clinician CSSA Score ≤20, (%) | 35 | 30 | 36 | 28 | 43 |
| Clinician CSSA Score >20, (%) | 65 | 70 | 64 | 72 | 57 |
| SCID (%) | |||||
| History Alcohol Dependence | 88 (52) | 20 (50) | 21 (47) | 21 (54) | 26 (55) |
| Current Alcohol Dependence*** | 30 (18) | 5 (13) | 5 (11) | 9 (23) | 11 (23) |
| History Sedative Dependence | 31 (18) | 6 (15) | 8 (18) | 7 (18) | 10 (21) |
| History THC Dependence**** | 72 (42) | 13 (33) | 14 (31) | 16 (41) | 29 (62) |
| Current THC Dependence | 18 (25) | 1 (8) | 5 (36) | 4 (25) | 8 (28) |
| Antisocial Personality Disorder | 46 (27) | 10 (25) | 10 (22) | 12 (31) | 14 (30) |
| ASI (past 30 days drug use), M (SD) | |||||
| Alcohol | 4.8 (8.3) | 3.6 (8.1) | 4.5 (7.9) | 6.4 (10.2) | 4.6 (7.1) |
| Heroin | 22.1 (12.0) | 20.3 (13.3) | 20.8 (13.1) | 24.3 (11.2) | 23.2 (10.4) |
| Cocaine | 20.8 (9.0) | 20.7 (8.8) | 21.6 (9.4) | 19.8 (8.9) | 20.9 (9.1) |
| Methadone | 8.2 (12.2) | 10.2 (13.6) | 9.5 (12.4) | 6.9 (12.3) | 6.5 (10.6) |
| Sedatives | 0.3 (0.8) | 0.2 (0.5) | 0.3 (0.8) | 0.2 (0.6) | 0.5 (1.0) |
| THC | 2.7 (7.1) | 0.5 (1.8) | 2.7 (7.2) | 2.7 (7.6) | 4.4 (8.9) |
*
Where numbers add up to more than 100, it is due to rounding errors.
**
These participants were on Methadone Maintenance prior to study admission.
***
A two-factor analysis revealed that participants receiving placebo were significantly more likely to be alcohol dependent that participants receiving TOP.
***
One participant’s data missing for this diagnosis.