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. Author manuscript; available in PMC: 2016 May 21.
Published in final edited form as: Chem Soc Rev. 2015 Mar 17;44(10):3036–3055. doi: 10.1039/c5cs00020c

Figure 11.

Figure 11

Molecular beacons used for detection of biomolecules on a solid surface. (A) Working principle of the triplex molecular beacon-based DNA nanomachine-directed reversible SERS-active substrate and corresponding reversible SERS “hot-spot” generation through assembly and disassembly of AgNPs on a gold film surface. Reprinted with permission from ref. 123. Copyright (2012) American Chemical Society. (B) Schematic representation of the AuNP sensor with hydrophobic molecular beacons. Reprinted with permission from ref. 125. Copyright (2014) Royal Society of Chemistry.