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. Author manuscript; available in PMC: 2015 May 14.
Published in final edited form as: Am J Psychiatry. 2014 Jan;171(1):72–81. doi: 10.1176/appi.ajp.2013.12081103

Table 1. Linkage Peaks with PPL > 0.35 from All Analyses.

------Maximizing Model------

Phenotype Chr cM PPL Band range Width (Mb) LOD -/- +/- +/+ DGF α
YBOCS 13 58 0.36 q14.3-21.3 17.3 4.2 -3.0 0.0 3.0 0.300 0.7
SRS-DT 14 117 0.37 q32.2-32.23 7.6 3.5 0.00 0.10 0.80 0.100 1.0
LI* 15 83 0.57 q23-26.2 24.2 4.1 0.00 0.70 0.99 0.001 1.0
SRS-QT 15 120 0.52 q26.2-26.3 6.2 4.5 -2.0 1.0 2.0 0.100 0.9
RI* 16 43 0.36 p12.1-12.3 8.9 4.6 0.00 0.00 0.90 0.200 1.0

PPL is the posterior probability of linkage. LOD is the fully maximized LOD score, sometimes referred to as a MOD score. -/-, +/-, and +/+ are the estimated genotypic effects for the locus; for categorical analysis these quantities are penetrances and for quantitative traits they are genotypic means on a z-score scale. DGF is the disease gene frequency and α is the heterogeneity parameter in the admixture likelihood at the maximizing model.

Phenotypes are: YOBCS=Yale-Brown Obsessive Compulsive Scale, SRS-DT=Social Responsiveness Scale- Dichotomous trait, LI*=Oral Language Impairment and/or ASD, SRS-QT=Social Responsiveness Scale-Quantitative Trait, RI*= Written Language (Reading) Impairment and/or ASD.