Table 2. Relative gene expression of potential correlates in co-cultures using splenocytes from differentially vaccinated BALB/cByJ, BKO, and C57BL/6J mice.
| BALB/cByJ | BKO | C57BL/6J | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| LVS | LVS-G | LVS-R | HK-LVS | LVS | LVS-G | LVS-R | HK-LVS | LVS | LVS-G | LVS-R | HK-LVS | |
| IFN-γ | 43 | 59 | 56 | 2.0 | 16 | 43 | 76 | 0.6 | 89 | 93 | 89 | 0.9 |
| TNF-α | 1.7 | 1.8 | 1.8 | 1.2 | 2.3 | 1.9 | 1.9 | 1.2 | 1.9 | 1.8 | 1.6 | 0.8 |
| IL-6 | 1.2 | 1.5 | 1.9 | 1.9 | 0.1 | 0.7 | 0.7 | 0.7 | 2.7 | 6.1 | 4.3 | 0.9 |
| IL-12rβ2 | 2.8 | 2.1 | 2.1 | 1.2 | 1.0 | 2.4 | 2.2 | 0.9 | 5.0 | 3.6 | 4.5 | 1.2 |
| IL-18bp | 6.8 | 4.0 | 1.9 | 1.0 | 5.9 | 3.3 | 2.9 | 0.9 | 3.2 | 2.1 | 2.6 | 1.1 |
| IL-27 | 9.2 | 4.4 | 3.7 | 1.3 | 3.5 | 2.9 | 2.7 | 1.0 | 2.5 | 3.0 | 2.7 | 0.9 |
| GM-CSF | 3.3 | 3.9 | 5.2 | 1.3 | 1.4 | 4.6 | 7.5 | 0.6 | 9.1 | 5.6 | 6.0 | 0.9 |
| T-bet | 2.9 | 3.2 | 3.8 | 1.4 | 2.9 | 2.1 | 2.4 | 0.8 | 4.4 | 4.0 | 3.5 | 1.1 |
| IL-22 | 1.0 | 1.4 | 2.3 | 1.6 | 0.5 | 1.0 | 2.2 | 0.7 | 2.7 | 1.7 | 4.1 | 0.9 |
| CCL7 | 0.6 | 1.0 | 1.2 | 1.1 | 0.3 | 0.7 | 0.9 | 0.6 | 0.8 | 0.9 | 0.4 | 1.0 |
| Irf-1 | 1.2 | 1.2 | 1.5 | 1.2 | 2.3 | 2.1 | 1.3 | 1.1 | 1.3 | 1.4 | 1.4 | 1.0 |
| SOCS-1 | 2.1 | 2.2 | 3.0 | 1.6 | 2.4 | 1.3 | 2.5 | 0.9 | 2.7 | 1.6 | 2.1 | 1.2 |
| CCR5 | 6.55 | 6.9 | 3.3 | 1.2 | 9.55 | 4.7 | 2.9 | 1.5 | 2.4 | 1.3 | 1.3 | 1.2 |
Values indicate median fold change of the indicated genes, compared to naive cells; values derived from analyses of splenocytes of BALB/cByJ, BKO, and C57BL/6J mice were calculated from seven, four, and four independent experiments, respectively.