Table 2. Stress-induced % change in compounds.
| Compound name and pathway | Pre-stress: median (frstqrt, thrdqrt) | Post-stress median (frstqrt, thrdqrt) | % change: median (frstqrt, thrdqrt) | p value |
|---|---|---|---|---|
| Tyrosine | ||||
| Tyrosine | 93.84 (75.08, 119.77) | 84.57 (71.43, 108.15) | −11.71 (−15.60, −6.21) | <.001 |
| 4-Hydroxyphenyllactic acid | 88.62 (75.60, 107.89) | 83.58 (70.02, 112.59) | −3.46 (−6.3, 4.61) | 0.19 |
| 4-Hydroxybenzoic acid | 53.80 (20.41, 130.28) | 53.21 (18.3, 133.76) | −2.72 (−10, 5.49) | 0.27 |
| Homogentisic acid | 67.88 (55.90, 106.78) | 61.04 (44.72, 91.53) | −11.05 (−27.42, −1.23) | <.001 |
| Methoxy-hydroxyphenly glycol | 87.71 (75.10, 111.06) | 95.89 (77.16, 109.87) | .65 (−5.77, 7.51) | 0.54 |
| Homovanillic acid | 80.34 (66.71, 104.77) | 73.49 (54.85, 92.10) | −9.40 (−21.03, −1.87) | 0.014 |
| Tryptophan | ||||
| Tryptophan | 99.46 (85.02, 105.25) | 94.72 (80.14, 99.52) | −3.66 (−7.66, .01) | 0.003 |
| 5-hydroxytryptophan | 1.1 (.1, 2.16) | 1.18 (.1, 1.94) | 0 (−12.61, 3.73) | 0.68 |
| Serotonin | 76.85 (36.46, 122.42) | 85.31 (47.47, 135.1) | 8.79 (−22.65, 62.49) | 0.14 |
| 5-Hydroxyindoleacetic acid | 75.17 (56.56, 110.81) | 75.14 (51.02, 101.18) | −5.63 (−18.66, 6.03) | 0.27 |
| N-acetylserotonin | 81.56 (63.49, 111.94) | 76.99 (66.94, 103.72) | −4.6 (−7.67, .17) | 0.022 |
| Kynurenine | 98.24 (87.9, 111.78) | 93.60 (83.37, 109.83) | −3.92 (−8.86, .23) | 0.003 |
| 3-Hydroxykynurenine | 90.04 (71.40, 118.61) | 79.92 (62.76, 100.64) | −9.2 (−13.34, −1.59) | <.001 |
| 3-Hydroxyanthranillic acid | 4.48 (.10, 53.71) | 3.13 (.10, 45.81) | 0 (−14.71, 6.42) | 0.84 |
| Indole-3-lactic acid | 85.50 (65.22, 115.03) | 76.24 (59.43, 108.56) | −8.54 (−13.37, −5.48) | <.001 |
| Indole-3-propionic acid | 68.68 (41.64, 125.43) | 64.27 (42.58, 92.46) | −3.50 (−9.98, 3.60) | 0.14 |
| Purine | ||||
| Hypoxanthine | 71.41 (59.75, 88.94) | 87.17 (73.49, 106.56) | 16.34 (−2.0, 33.26) | 0.009 |
| Xanthine | 83.54 (70.68, 108.52) | 87.64 (68.61, 110.82) | −1.31 (−6.14, 13.51) | 0.88 |
| Uric Acid | 94.80 (90.10, 102.64) | 93.96 (87.01, 103.10) | −.86 (−2.89, .84) | 0.053 |
| One-carbon metabolism | ||||
| Methionine | 97.3 (77.7, 111.96) | 86.23 (71.27, 100.12) | −10.54 (−17.60, −5.31) | <.001 |
| Tocopherol | ||||
| Tocopherol-gamma | 45.73 (31.95, 98.20) | 42.62 (25.95, 83.52) | −9.81 (−35.19, 5.38) | 0.17 |
| Tocopherol-alpha | 72.52 (47.46, 80.57) | 64.86 (38.70, 83.69) | −11.47 (−33.51, 12.54) | 0.23 |