Fig 1. SBP1 induction in nude mice inhibited tumor growth of xenografts.
(A) SBP1 induced by doxycycline in HCT116-TetSBP1 cells were validated by immunoblot analysis. (B) Photographs illustrate representative tumors in xenografts with SBP1 induction (TetSBP1, right) compared to tumors without SBP1 induction (Act, left). 10 mice in total. (C-D) SBP1 induction results in a decline of tumor volume and weight. Results were analyzed with Student’s t-test and shown as mean±SD. **P<0.01.