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. 2015 May 14;10(5):e0126285. doi: 10.1371/journal.pone.0126285

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© 2015 Ying et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 2 — (A) Representative images of lungs and hematoxylin and eosin (HE)-staining of lungs isolated from mice that received tail vein injection of HCT116-Act cells (Act) and HCT116-TetSBP1 cells (TetSBP1). Each group contains 5 mice. Arrows illustrates the visible nodules and metastatic nodules in lung. Scale bar = 200 μm. (B) SBP1 induction inhibits tumor metastasis in vivo. The numbers of pulmonary metastatic nodules were counted under microscope and analyzed with Student’s t-test. Results are shown as mean±SD. **P<0.01.