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. 2015 May 14;10(5):e0126582. doi: 10.1371/journal.pone.0126582

Fig 2. Gene expression in PBMCs from 20 patients with IgG4-RD, before and after steroid treatment.

Fig 2

(A) CLC; Charcot—Leyden crystal protein. (B) IL8RA; interleukin 8 receptor alpha. (C) IL8RB; interleukin 8 receptor beta. (D) MS4A3; membrane-spanning 4-domain subfamily A member 3. (E) DEFA3; defensin alpha 3. (F) DEFA4; defensin alpha 4. Levels of CLC, IL8RA and IL8RB mRNA were not altered in IgG4-RD patients by steroid therapy (A-C), whereas those of MS4A3, DEFA3 and DEFA4 were significantly increased following steroid therapy (D-F, p<0.01).