Table 2. Profiles of IgG4-RD patients assayed by Real time RT-PCR.
No | Age | Sex | IgG (mg/dL) | IgG4 (mg/dL) | IgG4(postTx) | IgE (IU/mL) | Lesion |
---|---|---|---|---|---|---|---|
1* | 66 | M | 5,630 | 3,120 | 291 | 265 | SG, DD, LN |
2* | 63 | M | 2,950 | 1,540 | 184 | 7 | SG, BD, PC, PS |
3 | 69 | F | 1,950 | 362 | 44 | 151 | SG |
4 | 62 | M | 1,500 | 435 | 89 | 301 | SG, PC, LN |
5 | 60 | F | 1,150 | 110 | 12 | 399 | LG, SG, PC |
6 | 79 | M | 4,020 | 1,460 | 98 | 330 | SG, RF, KN, PS, LN |
7 | 70 | M | 2,563 | 1,160 | 326 | 283 | SG, RF, IP, UR |
8 | 65 | M | 6,786 | 3,880 | 447 | 673 | PS, LN |
9 | 72 | M | 2,980 | 254 | 9 | 85 | PL, RF, PC, PG, LN |
10 | 73 | M | 3,377 | 1,770 | 690 | 1,216 | SG, PC |
11 | 47 | F | 1,365 | 304 | 35 | 238 | LG, SG |
12 | 66 | M | 1,679 | 756 | 153 | 631 | SG, IP |
13 | 53 | M | 1,692 | 313 | 55 | 494 | LG, UR |
14 | 70 | M | 2,090 | 314 | 201 | 190 | LG, SG |
15 | 52 | F | 3,038 | 1,300 | 298 | 327 | LG, SG |
16 | 38 | M | 2,861 | 1,440 | 315 | 219 | LG, IP |
17 | 66 | F | 3,214 | 1,370 | 174 | 60 | LG, SG, IP, BD |
18 | 66 | F | 4,174 | 1,300 | 179 | 100 | LG, SG, RF, IP, LN |
19 | 59 | M | 1,603 | 499 | 124 | 1,139 | RF |
20 | 59 | M | 2,456 | 1,430 | 226 | 262 | PC, IP |
21 | 74 | M | 3,250 | 788 | 189 | AA, LN | |
22 | 91 | M | 4,577 | 669 | 626 | SG | |
23 | 55 | M | 3,087 | 1,760 | 837 | PS, IP | |
24 | 57 | F | 2,442 | 990 | 1,181 | SG | |
25 | 68 | F | 1,620 | 419 | 159 | SG, PC | |
26 | 71 | M | 1,800 | 373 | 180 | SG, PC, LN | |
27 | 56 | M | 4,010 | 2,160 | 680 | LG, SG, LN |
Real time RT-PCR was performed on mRNA samples isolated from the PBMCs of 27 patients (19 men, 8 women; median age 66 years) with IgG4-RD. Case 1* and 2* are the same patients in Table 1. Patients with steroid treatment are Case1 to Case 20, and IgG4 (post Tx) means the value of serum IgG4 after steroid treatment. Abbreviations: SG, salivary gland; DD, duodenum; LN, lymph node; BD, bile duct; PC, pancreas; PS, prostate; AA, aorta abdominalis; IP, interstitial pneumonia; LG, lacrimal gland; RF, retroperitoneal fibrosis; KN, kidney; UR, ureter; PL, pleura; PG, pituitary gland.