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. 2015 May 14;10(5):e0127020. doi: 10.1371/journal.pone.0127020

Fig 2. Representative images of staining for alpha-sma (marker for ULP IC) showing the increased thickness of the alpha-sma+ ULP IC area in MS and BPS bladders.

Fig 2

The ULP IC area lies between the 2 dotted red lines. The alpha-sma+ cell-types under the ULP IC area are MM-fibres and perivascular smooth muscle cells (which were excluded from analysis); IC in the DLP are negative for alpha-sma. In BPS bladder heavy inflammatory infiltrate is laying in between the IC, while in MS bladder this infiltrate is less pronounced. U is urothelium, ULP IC equals upper lamina propria interstitial cell. Scale bars indicate 600μm.