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. Author manuscript; available in PMC: 2015 May 14.
Published in final edited form as: Cell Rep. 2015 Apr 30;11(6):957–966. doi: 10.1016/j.celrep.2015.04.009

Figure 4.

Figure 4

TRIF and MAVS mediated PSM induced IFN-I activation.

(A–D) PSM-induced changes of Ifn-α4 and Ifn-β gene expression in BMDCs infected with lentiviruses carrying shRNAs targeting the indicated genes.

(E–H) PSM-induced changes of Ifn-α4 and Ifn-β gene expression in BMDCs isolated from wild-type or gene knockout mice.

(I) PSM-induced RANTES production in BMDCs isolated from wild-type or gene knockout mice.

(L) Schematic view of PSM-induced signaling pathway that mediates IFN-I activation.

Data are presented as mean ± S.D. *, P<0.05, **, P<0.01. See also Figure S4.