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. Author manuscript; available in PMC: 2016 May 12.
Published in final edited form as: Cell Rep. 2015 Apr 30;11(6):910–920. doi: 10.1016/j.celrep.2015.04.006

Figure 7. The Mutations M531R and S532P Are Likely to Cause Local Structural Changes with a Major Impact on the Actin-Myosin Interaction.

Figure 7

Local environments of M531 (green) and S532 (orange) correlate with the sequence conservation profiles in Figure S6. Both positions are on an α helix in close proximity to a patch of negatively charged residues (red) on actin. M531 (green) is buried in the hydrophobic core, and S532 (orange) is exposed to solvent. See also Figure S5.