FIG 6.

Graphic representation of the selectivity profile of BCV for inhibition of BKPyV in HUCs. (A) EC₉₀, EC₅₀, CC₉₀, and CC₅₀ of BCV. (B) SI₅₀ and SI₉₀. The icBKPyV and endpoint viability were measured at 72 hpi/hpt. EC₉₀ and CC₉₀ values and their 95% confidence intervals were calculated using the curve-fitting software XLfit with a 4-parameter logistic model (model 208). Selectivity indices were calculated by dividing CC by EC. Confidence intervals for selectivity indices were calculated as follows: lower limit = (CC_x – 95% CI)/(EC_x + 95% CI); upper limit = (CC_x + 95% CI)/(EC_x – 95% CI).