FIG 1.

Two-phase elimination model of total and unbound plasma ATV and DTG concentrations in a mother with HIV infection and her infant. Shown are maternal plasma ATV (triangles) and DTG (squares) concentrations 2 days before delivery, neonate plasma ATV (triangles) and DTG (squares) concentrations, and extrapolated plasma ATV (dashed triangle) and DTG (dashed circle) concentrations at delivery in cord blood. Elimination half-lives of DTG were determined by linear regression. The limit of quantification (LOQ) of ATV and DTG is 10 ng/ml. By convention, values below the LOQ were plotted as LOQ/2.