TABLE 1.
Baseline characteristics of participants in studies 1 and 2
| Characteristic | Study 1 | Study 2 | Combined |
|---|---|---|---|
| n | 15 | 76 | 91 |
| Wt (median [IQR]) (kg)a | 10.3 (9.8–14.0) | 12.0 (10.0–13.7) | 12.0 (10.0–13.8) |
| Age (median [IQR]) (yr) | 3.4 (1.6–4.0) | 2.7 (1.8–3.5) | 2.8 (1.8–3.5) |
| Male (no. [%]) | 7 (44) | 36 (47) | 43 (47) |
| Ht (median [IQR]) (cm) | 82 (75–92) | 87 (81–93) | 87 (79–93) |
| Baseline parasitemia (median [IQR]) (no. of parasites/μl) | 19,660 (13,710–26,310) | 52,775 (20,047–193,669) | 41,383 (16,805–141,834) |
| Admission temp (median [IQR]) (°C) | 38.1 (37.6–38.9) | 38.7 (37.8–39.5) | 38.7 (37.8–39.4) |
| Severe malaria (no. [%]) | 10 (63) | 48 (63) | 58 (63) |
| Vomiting at admission (no. [%]) | 2 (13) | 46 (61) | 48 (52) |
| Blantyre coma score (no. [%]) of: | |||
| 1 | 0 (0) | 2 (3) | 2 (2) |
| 2 | 0 (0) | 0 (0) | 0 (0) |
| 3 | 1 (6) | 7 (9) | 8 (9) |
| 4 | 2 (13) | 7 (9) | 9 (10) |
| 5 | 13 (81) | 60 (79) | 73 (79) |
a
IQR, interquartile range.