FIG 1.

Time-kill kinetics of polymyxin B (A) and T9W (B) against P. aeruginosa 27853 and of T9W against P. aeruginosa LCCI (C), P. aeruginosa LCGE (D), and P. aeruginosa LCCE (E) at 0× LC (filled diamonds), 1× LC (open squares), 2× LC (open triangles), and 4× LC (open circles). Dilutions of aliquots taken from 0 to 30 min were plated on MH agar. The graphs were derived from average values of three independent trials. ∗∗, P < 0.001, compared to the value for the control at the same concentration.