FIG 4.

HIV-1 mutant-versus-mutant growth competitions (genotype indicated): IN-E92Q versus RT-M184V + IN-E92Q in the presence of EVG at 1 nM (A) and 100 nM (B) and IN-E92Q versus RT-K65R/M184V + IN-E92Q in the presence of EVG at 1 nM (C) and 100 nM (D). The data shown are averages from 3 independent competition experiments with standard deviations. Mean relative fitness (RF; 1 + s) values for the double and triple mutant viruses (filled circles) relative to the IN-E92Q mutant (open circles) are shown in Table 2.