TABLE 1.
Study population characteristics for 12 patients with multidrug-resistant pulmonary tuberculosis
| Parameter | Valuea (n = 12) |
|---|---|
| Demographic characteristics | |
| Male sex | 11 (92) |
| Age, yr | 33.5 (17–54) |
| Georgian ethnicity | 10 (84) |
| Diabetes mellitus | 2 (17) |
| Hepatitis C | 5 (42) |
| Alcohol user | 1 (8) |
| Tobacco user | 5 (42) |
| Prior treatment for tuberculosis | 3 (25) |
| Wt, kg | 68 (49–100) |
| Body mass index, kg/m2 | 22.6 (17–33) |
| Cavity diam, cm | 2.8 (2.1–10.0) |
| Laboratory values | |
| Creatinine clearance,b ml/min | 117.7 (81–143) |
| Albumin level, g/dl | 4.4 (3.5–4.9) |
| Hemoglobin level, g/dl | 12.8 (12.1–13.5) |
| Alanine aminotransferase level, U/liter | 30.5 (10–125) |
| Treatment | |
| Type of surgery | |
| Segmentectomy | 6 (50) |
| Lobectomy | 6 (50) |
| Levofloxacin dose | |
| 750 mg | 10 (83) |
| 1,000 mg | 2 (17) |
| Levofloxacin, mg/kg | 11.8 (7.5–15.3) |
| Days receiving levofloxacin | 372 (15–810) |
a
Data are presented either as number (percentage) or as median value (range).
b
Using the Cockcroft-Gault equation.