FIG 3.

Serum bactericidal activity of O25b MAbs. Bactericidal effect was expressed as percent reduction of CFU relative to the bacterial numbers recovered from the control (irrelevant MAb) group. (A) Bacteria grown in LB broth incubated with humanized MAbs for 3 h. Combined results of 3 independent experiments shown as means ± standard errors. (B) Bacteria grown in 50% depleted heat-inactivated human serum incubated with humanized MAbs for 5 h. Combined results of 2 independent experiments shown as ranges (B).