. 2015 May 14;59(6):3109–3116. doi: 10.1128/AAC.04494-14

TABLE 1.

Binding of O25b MAbs to the cognate antigen (O25b polysaccharide), expressed as affinity, association, and dissociation constants, and binding to unrelated antigens, expressed as response values

MAb	K_d (M⁻¹)	k_on (M⁻¹s⁻¹)	k_off (s⁻¹)	Polyreactivity response (nm)
MAb	K_d (M⁻¹)	k_on (M⁻¹s⁻¹)	k_off (s⁻¹)	Dextran	DNA	Fetuin	Gelatin
3E9 chimeric	5.56E–08	2.83E+05	1.57E–02	−0.0114	−0.0114	−0.0076	−0.0159
3E9-11	6.94E–08	2.44E+05	1.69E–02	−0.0124	−0.0183	−0.0145	−0.016
2A7 chimeric	1.12E–07	1.42E+05	1.59E–02	−0.0178	−0.0175	−0.0146	−0.0161
2A7-01	1.15E–07	1.62E+05	1.86E–02	−0.0151	−0.0157	−0.0163	−0.0165
4D5 chimeric	1.49E–08	4.36E+04	6.51E–04	−0.0107	−0.0033	−0.0034	0.0024
4D5-02	3.82E–08	3.86E+04	1.47E–03	−0.0182	−0.0143	−0.0144	−0.0167
Irrelevant control MAb				0.0056	0.0121	−0.0224	−0.0164