Table 2. Markers associated with ERG expression.
Group | Protein or factor | Binary ERG | Mean Bin ERG | |
---|---|---|---|---|
| ||||
M-W p-value# | r | p-value$ | ||
MYC | MYC | <.001 | 0.437 | <.001 |
PIM2 | 0.001 | 0.231 | 0.002 | |
| ||||
PI3K/AKT | PTEN | 0.004 | -0.224 | 0.007 |
INPP4B | 0.002 | -0.140 | 0.011 | |
P-AKT | 0.005 | 0.195 | 0.003 | |
P-GSK3B | 0.022 | 0.244 | <.001 | |
| ||||
NFkB | NFkB p65 | 0.001 | 0.303 | <.001 |
NFkB P-S536 | <.001 | 0.316 | <.001 | |
| ||||
Transcription | p53 | 0.013 | 0.257 | <.001 |
SRF | <.001 | 0.344 | <.001 | |
SRC1 | 0.008 | 0.207 | 0.004 | |
| ||||
Signal transduction | Sprouty1 | 0.002 | 0.244 | 0.001 |
Mann-Whitney U test comparing expression in ERG negative versus ERG positive.
Spearman rank correlation and associated p-value.