TABLE 3.
Twin isolates
ELISA reactivity and 16 S rRNA sequence comparisons for mAb 260.8-reactive isolates from twin pairs and mothers enrolled in the Missouri Adolescent Female Twin Study are shown. ID, nucleotide sequence identity; RDP, Ribosomal Database Project; MZ, monozygotic; DZ, dizygotic.
| Family | Family ID-relationship | Isolate ID | Percent ID to VPI-5482 16 S rRNA | Percentage of VPI-5482 260.8 ELISA | Percentage of VPI-5482 225.4 ELISA | Percent ID to best hit in RDP |
|---|---|---|---|---|---|---|
| 1 | TS19-MZ twin | APG1.1 | 98.2 | 52 | 0 | 98 |
| 1 | TS19-MZ twin | APG1.2 | 98.0 | 59 | 1 | 98 |
| 1 | TS19-MZ twin | APG4.10 | 97.8 | 78 | 0 | 98 |
| 1 | TS19-MZ twin | APG4.11 | 97.9 | 88 | 0 | 98 |
| 1 | TS19-MZ twin | APG4.12 | 97.5 | 71 | 0 | 97 |
| 1 | TS19-MZ twin | APG4.13 | 98.1 | 91 | 1 | 98 |
| 1 | TS19-MZ twin | APG4.14 | 97.4 | 57 | 3 | 97 |
| 1 | TS19-MZ twin | APG4.3 | 97.8 | 50 | 3 | 98 |
| 1 | TS19-MZ twin | APG4.5 | 97.8 | 64 | 0 | 97 |
| 1 | TS19-MZ twin | APG4.6 | 98.0 | 62 | 1 | 97 |
| 1 | TS19-MZ twin | APG4.7 | 97.8 | 79 | 0 | 97 |
| 1 | TS19-MZ twin | APG4.9 | 98.1 | 79 | 0 | 98 |
| 1 | TS20-MZ twin | APG2.1 | 99.1 | 95 | 0 | 98 |
| 1 | TS20-MZ twin | APG2.10 | 99.1 | 92 | 0 | 99 |
| 1 | TS20-MZ twin | APG2.11 | 99.3 | 91 | 0 | 99 |
| 1 | TS20-MZ twin | APG2.13 | 97.8 | 105 | 0 | 97 |
| 1 | TS20-MZ twin | APG2.2 | 99.8 | 75 | 0 | 99 |
| 1 | TS20-MZ twin | APG2.3 | 98.9 | 91 | 0 | 98 |
| 1 | TS20-MZ twin | APG2.4 | 99.2 | 91 | 0 | 98 |
| 1 | TS20-MZ twin | APG2.5 | 99.8 | 99 | 0 | 99 |
| 1 | TS20-MZ twin | APG2.6 | 98.6 | 99 | 1 | 97 |
| 1 | TS20-MZ twin | APG2.7 | 99.8 | 88 | 0 | 99 |
| 1 | TS20-MZ twin | APG2.8 | 99.7 | 86 | 0 | 99 |
| 1 | TS20-MZ twin | APG2.9 | 98.8 | 93 | 0 | 97 |
| 1 | TS21-mother | APG2.2 | 98.2 | 106 | 0 | 97 |
| 1 | TS21-mother | APG3.3 | 98.6 | 112 | 0 | 98 |
| 1 | TS21-mother | APG5.6 | 98.6 | 110 | 0 | 98 |
| 1 | TS21-mother | APG5.7 | 98.3 | 106 | 0 | 97 |
| 1 | TS21-mother | APG5.8 | 98.3 | 91 | 0 | 97 |
| 1 | TS21-mother | APG5.9 | 98.6 | 106 | 0 | 98 |
| 1 | TS21-mother | APG6.10 | 96.9 | 86 | 0 | 96 |
| 2 | TS130-MZ twin | APG1.2 | 99.6 | 50 | 0 | 99 |
| 2 | TS130-MZ twin | APG1.3 | 99.6 | 67 | 0 | 99 |
| 2 | TS130-MZ twin | APG1.4 | 99.6 | 53 | 0 | 99 |
| 2 | TS130-MZ twin | APG1.6 | 99.6 | 40 | 0 | 99 |
| 2 | TS131-MZ twin | APG1.1 | 99.0 | 81 | 0 | 98 |
| 2 | TS131-MZ twin | APG1.2 | 98.8 | 85 | 0 | 98 |
| 2 | TS131-MZ twin | APG1.3 | 98.9 | 78 | 0 | 98 |
| 2 | TS131-MZ twin | APG1.4 | 99.0 | 34 | 0 | 98 |
| 2 | TS131-MZ twin | APG1.5 | 99.2 | 105 | 0 | 99 |
| 2 | TS131-MZ twin | APG1.6 | 98.9 | 36 | 0 | 98 |
| 2 | TS131-MZ twin | APG1.7 | 99.0 | 38 | 0 | 98 |
| 2 | TS131-MZ twin | APG1.8 | 99.0 | 63 | 0 | 98 |
| 2 | TS131-MZ twin | APG1.9 | 99.1 | 38 | 0 | 99 |
| 2 | TS132-mother | APG1.1 | 99.0 | 103 | 0 | 98 |
| 2 | TS132-mother | APG1.10 | 99.1 | 79 | 0 | 99 |
| 2 | TS132-mother | APG1.2 | 99.1 | 106 | 0 | 98 |
| 2 | TS132-mother | APG1.3 | 99.3 | 117 | 0 | 99 |
| 2 | TS132-mother | APG1.4 | 99.1 | 118 | 0 | 98 |
| 2 | TS132-mother | APG1.5 | 99.1 | 111 | 0 | 99 |
| 2 | TS132-mother | APG1.6 | 99.0 | 93 | 0 | 99 |
| 2 | TS132-mother | APG1.7 | 99.1 | 117 | 1 | 99 |
| 2 | TS132-mother | APG1.8 | 99.2 | 108 | 1 | 99 |
| 2 | TS132-mother | APG1.9 | 98.9 | 114 | 0 | 98 |
| 3 | TS118-DZ twin | APG1.1 | 99.7 | 127 | 0 | 99 |
| 3 | TS118-DZ twin | APG1.10 | 99.5 | 116 | 0 | 99 |
| 3 | TS118-DZ twin | APG1.11 | 99.9 | 111 | 0 | 99 |
| 3 | TS118-DZ twin | APG1.12 | 99.9 | 66 | 0 | 99 |
| 3 | TS118-DZ twin | APG1.14 | 99.7 | 99 | 0 | 99 |
| 3 | TS118-DZ twin | APG1.15 | 99.8 | 91 | 0 | 99 |
| 3 | TS118-DZ twin | APG1.16 | 99.7 | 117 | 1 | 99 |
| 3 | TS118-DZ twin | APG1.2 | 99.7 | 84 | 0 | 99 |
| 3 | TS118-DZ twin | APG1.3 | 99.8 | 80 | 0 | 99 |
| 3 | TS118-DZ twin | APG1.5 | 99.9 | 91 | 0 | 99 |
| 3 | TS118-DZ twin | APG1.6 | 99.7 | 125 | 0 | 99 |
| 3 | TS118-DZ twin | APG1.7 | 99.9 | 99 | 1 | 99 |
| 3 | TS118-DZ twin | APG1.8 | 99.7 | 110 | 0 | 99 |
| 3 | TS118-DZ twin | APG1.9 | 99.5 | 112 | 1 | 99 |
| 3 | TS119-DZ twin | APG1.1 | 99.1 | 71 | 4 | 98 |
| 3 | TS119-DZ twin | APG1.3 | 99.7 | 60 | 0 | 99 |
| 3 | TS120-mother | APG1.1 | 99.4 | 85 | 1 | 99 |
| 3 | TS120-mother | APG1.2 | 97.3 | 88 | 2 | 96 |
| 4 | TS1-MZ twin | APG1.01 | 99.7 | 86 | 99 | |
| 4 | TS1-MZ twin | APG1.02 | 99.6 | 83 | 1 | 99 |
| 4 | TS1-MZ twin | APG1.03 | 99.7 | 92 | 0 | 99 |
| 4 | TS1-MZ twin | APG1.04 | 99.8 | 75 | 0 | 99 |
| 4 | TS1-MZ twin | APG1.05 | 99.7 | 89 | 0 | 99 |
| 4 | TS1-MZ twin | APG1.06 | 99.6 | 105 | 0 | 99 |
| 4 | TS3-mother | APG1.03 | 99.8 | 102 | 0 | 99 |
| 4 | TS3-mother | APG1.05 | 99.8 | 16 | 0 | 99 |
| 4 | TS3-mother | APG1.06 | 99.8 | 96 | 0 | 99 |
| 4 | TS3-mother | APG1.07 | 99.8 | 34 | 0 | 99 |
| 5 | TS61-DZ twin | APG1.1 | 99.6 | 62 | 21 | 99 |
| 5 | TS61-DZ twin | APG1.10 | 99.6 | 123 | 74 | 99 |
| 5 | TS61-DZ twin | APG1.4 | 99.6 | 95 | 14 | 99 |
| 5 | TS61-DZ twin | APG1.5 | 99.6 | 122 | 178 | 99 |
| 5 | TS61-DZ twin | APG1.6 | 99.6 | 98 | 17 | 99 |
| 5 | TS61-DZ twin | APG1.7 | 99.4 | 119 | 125 | 99 |
| 5 | TS61-DZ twin | APG1.8 | 99.6 | 115 | 15 | 99 |
| 5 | TS61-DZ twin | APG1.9 | 99.6 | 99 | 101 | 99 |
| 5 | TS62-mother | APG1.1 | 99.8 | 41 | 0 | 99 |
| 5 | TS62-mother | APG1.2 | 99.8 | 71 | 0 | 99 |
| 6 | TS4-MZ twin | D6G4 | 94.5 | 29 | 0 | 99 |
| 6 | TS6-mother | A7 | 99.7 | 88 | 0 | 98 |