FIGURE 1.

Stability and structure of CagL. A, schematic ribbon of CagL structure solved at pH 4.5 showing the 6 helices from the N terminus (blue) to the C terminus (red). B, structure of the compact form of CagL^3zci. C, superposition of CagL^4cii (blue) onto the recent crystal structure, CagL^4x5u (red). The presence of α1 in the new structure causes straightening of the N-terminal half of α2 below the RGD motif (gray spheres). D, representation of the 2F_o − F_c σ_A-weighted electron density map contoured at 1.5 σ showing α1 residues of CagL.