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. 2015 May 15;5:10131. doi: 10.1038/srep10131

Figure 8.

Figure 8

Effects on meiotic initiation of fadrozole (F) in XX and E2 in XY tilapia. A-H, histological observations of gonads of fadrozole- and the E2-treated fish on meiotic initiation in the XX and XY tilapia. In the fadrozole-treated XX gonads, germ cells delayed meiotic initiation until 90 dah and resulted in female to male sex reversal with an testis exhibiting spermatogonia, spermatocytes and spermatids at 90 dah. By contrast, in the E2-treated XY gonads, meiotic initiation occurred earlier to 30 dah and resulted in male to female sex reversal with an ovary exhibiting oogonia, primary and secondary oocytes at 90 dah. OG, oogonia; OC, oocytes; SG, spermatogonia; SC, spermatocytes; ST, spermatids. Scale bar: 10 μm. I-K, the expression of aldh1a2, cyp26a1 and meiosis marker sycp3 in the control and the treated groups as shown by real-time PCR. Data were expressed as mean ± SD (n = 5). Different letters indicate statistical differences at P < 0.05 as determined by one-way ANOVA followed with a post-hoc test. F-XX, fadrozole-treated XX fish; E2-XY, E2-treated XY fish. Dah, days after hatching.