Figure 5. Kypho-lordotic deformity of the vertebral column in SB fetuses.
Skeletal preparations of the lumbar spinal region in a dorsolateral view of E18.5 mouse fetuses. Cranial is to the left, caudal to the right. Bone is stained red and cartilage is blue. Note the even curvature of the spine in a normal fetus (A) as opposed to the kypho-lordotic spinal deformity in a SB fetus (B). Double headed arrow marks the region of the SB lesion, whose cranial end has been marked with a single suture (white arrow). Scale bar: 480 μm (A,B).