Table 1.
Sample Demographic and Clinical Characteristics
| Variable | Overall N = 108 | Treatment assignment | p | |
|---|---|---|---|---|
| TNP n = 56 | VAR n = 52 | |||
| Demographics | ||||
| Age | 32.7±7.6 | 33.4±7.5 | 32.0±7.8 | .381 |
| Caucasian (n), % | 73.2 (79) | 71.4 (40) | 75.0 (39) | .676 |
| Education | ||||
| High school or less, % | 30.6 (33) | 28.6 (16) | 32.7 (17) | .419 |
| Some college, % | 37.0 (40) | 42.9 (24) | 30.8 (16) | |
| College or beyond, % | 32.4 (35) | 28.6 (16) | 36.5 (19) | |
| Marital status | ||||
| Never married, % | 37.4 (40) | 34.5 (19) | 40.4 (21) | .215 |
| Married/widowed, % | 33.6 (36) | 29.1 (16) | 38.5 (20) | |
| Separated/divorced, % | 29.0 (31) | 36.4 (20) | 21.1 (11) | |
| Menstrual phasea | ||||
| Follicular, % | 53.3 (56) | 56.6 (30) | 50.0 (26) | |
| Luteal, % | 46.7 (49) | 43.4 (23) | 50.0 (26) | .498 |
| Smoking characteristics | ||||
| Cigarettes per day | 17.0±7.3 | 16.6±6.7 | 17.4±7.8 | .779 |
| Years smoking | 14.3±7.7 | 14.4±7.8 | 14.2±7.7 | .796 |
| Age became regular smoker | 17.6±4.3 | 18.0±4.6 | 17.1±3.9 | .182 |
| Quit attempts | 3.3±3.6 | 3.2±3.6 | 3.4±3.6 | .617 |
| Last quit attempt (years) | 2.5±4.2 | 2.2±3.5 | 2.9±4.9 | .444 |
| Live with a smoker (n), % | 54.6 (59) | 62.5 (35) | 46.2 (24) | .088 |
| Carbon monoxide (CO) | 5.2±1.5 | 5.5±3.5 | 4.7±3.1 | .165 |
| FTND | 4.9±2.2 | 5.0±2.4 | 4.8±2.0 | .412 |
| QSU | 4.2±1.3 | 4.1±1.4 | 4.3±1.3 | .479 |
| Factor 1 | 5.2±1.5 | 5.1±1.6 | 5.3±1.5 | .977 |
| Factor 2 | 3.2±1.4 | 3.0±1.5 | 3.3±1.3 | .313 |
Data shown as mean ± standard deviation or % (n). FTND = Fagerström Test for Nicotine Dependence; QSU = Questionnaire of Smoking Urges; TNP = transdermal nicotine patches; VAR = varenicline.
aMenstrual phase at target quit date as determined by cycle days from self-reported menses. Specifically, follicular phase was defined as inclusive of the days between menses onset and 14 days post-menses onset whereas luteal phase was defined as days outside this range.